In any case though one of the best examples for thinking outside the box I have used with employees is the Doubt Helix by James Watson. You get a rare look into how two scientists along with Rosalind Franklin were able to use new techniques to leap ahead of the better funded efforts into discovering the structure of DNA. By adopting these new methods three unheralded scientists beat out Linus Pauling at CalTech, among others, to one of science's biggest prizes of the past century.
While there are some ethical discussions of Crick & Watson's use of Rosalind Franklin's work (see Rosalind Franklin and DNA
The Double Helix: A Personal Account of the Discovery of the Structure of DNA
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